Capparis himalayensis belonging to Capparidaceae grows widely in Xinjiang Uygur Autonomous Region and Tibet

widely in Xinjiang Uygur Autonomous Region and Tibet of China. Its root barks, leaves and fruits are used for the treatment of rheumatism in traditional medicine. Previous investigations have led to the isolation of different chemical components showing various bioactivities from the Capparis genus while up to now, there is no report regarding chemical constituents of this species. In the present study, we attempted to find some bioactive components from Capparis himalayensis to support its development as a medicinal resource. This paper describes the isolation and structural elucidation of two new alkaloids 6-methoxyl-2 -(methylthio)spiro[3H-indole-3,5 (4 H)thiazol]-2(1H)-one (1) and 6methoxy-2-(methylthio)-1H-indole-3-carbaldehyde (2) from the ethanol extract of the plant along with seven known compounds. The known compounds were identified as 6methoxyindoline-2,3-dione (3), wogonin (4), oroxylin A (5), kaempferol (6), apigenin (7), quercetin (8) and luteolin (9) by comparison of spectroscopic properties (MS, H-NMR, C-NMR, HMQC and HMBC). Among the known compounds, 3, 4, 5, 7, 9 were isolated from Capparis genus for the first time.